Researchers discover a way to sensitize glioblastoma to chemotherapy - News-Medical.net

Researchers discover a way to sensitize glioblastoma to chemotherapy News-Medical.net The key is a chemical called glutathione (GSH). The GSH pathway allows both healthy and cancerous cells to pump out toxins. The more GSH a cell makes, the more efficiently it can cleanse itself. Brain cancer cells may literally coat themselves with GSH ...

Neuroprotection - Drugs, Markets and Companies

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Selectively stopping glutathione sensitizes brain tumors to chemotherapy

( University of Colorado Denver ) Brain cancer cells are especially resistant to chemotherapy -- new research details the mechanism of this resistance and provides a powerful strategy for countering it.

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Researchers discover a way to sensitize glioblastoma to chemotherapy

Brain cancer cells are particularly resistant to chemotherapy - toxins enter the cells, but before the toxins can kill, cancer cells quickly pump them back outside. In fact, brain cancer cells are even better than healthy cells at cleaning themselves. This means that when hit with chemotherapy, healthy cells tend to die before brain cancer cells. Especially in the brain, killing healthy cells is ...